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15 The ABCSG 8 trial was a randomized, open label trial comparing 5 years of tamoxifen with 2 years of tamoxifen followed by 3 years of anastrozole in postmenopausal women with hormone receptor positive breast cancer, for whom formalin fixed, paraffin embedded blocks from the original tumors were collected to extract RNA and for use in a subsequent PAM50 analysis cialis prescription

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